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Pros & Cons
Pros
This promises to be life changing for me. The accumulation of senescent cells is one of the causes of aging. Laboratory research suggests that it may extend life-span, have anti-cancer activity and lessen complications of type 1 diabetes.
Tablet at 750mg means you can actually get 60 servings if you wanted(500mg is smallest effective dose for nitrosigine) tried this brand for seanol after reading dr sinatra.
Fisetin is a flavonol with antioxidant properties found in plants such as the japanese fruit wax tree (rhus succedanea) it is a natural flavonoid that has been shown to have antioxidant and anti-inflammatory properties, and it is believed to support b... Read More
Cons
Taking this supplement caused a headache. Also very sensitive gums and tooth pain. Fda has not endorsed it yet.
Highlights
Quality
It was actually fairly impressive, i had fleeting moments of the most profound and broad logical applications i think i have ev... Read More
Animal data shows fisetin to be a surprisingly effective senolyticit is exciting to see animal data arrive for some of the pote... Read More
During absorption through the small intestine and passage through the liver, fisetin and other flavonoids undergo chemical modi... Read More
If these errant cells can be removed, then inflammatory diseases and numerous aspects of aging can be turned back to some degree.
Price
You get 100mg fisetin x 30 caps = 3,000mg fisetin for $11.
Swanson gives you the same amount for $17.
But i did enough research to convince me to at least try it for $11.
Shipping
Keep in mind that i take other supplements daily but the package was delivered in the afternoon and it was taken hours after the others.
Competitiveness
This seems like a plausible goal, and may turn out to present meaningful competition to efforts such as those of oisin biotechn... Read More
Overview
- How are reviewers describing this item?
senescent and such. - Our engine has profiled the reviewer patterns and has determined that there is minimal deception involved.
- Our engine has determined that the review content quality is high and informative.
- Our engine has analyzed and discovered that 78.3% of the reviews are reliable.
- This product had a total of 1,216 reviews as of our last analysis date on Dec 17 2024.
Helpful InsightsBETA
Posted by a reviewer on Amazon
As a reminder the accumulation of senescent cells is one of the causes of aging countless cells become senescent every day in our bodies but near all are destroyed
Posted by a reviewer on Amazon
A tiny fraction linger to cause significant harm through the inflammatory signal molecules that they secrete
Posted by a reviewer on Amazon
If these errant cells can be removed then inflammatory diseases and numerous aspects of aging can be turned back to some degree
Posted by a reviewer on Amazon
Some senolytic compounds have been tested in animals but a larger body of candidate senolytic drugs are presently only accompanied by cell study data
Posted by a reviewer on Amazon
The ability to selectively destroy senescent cells in a petri dish does little more than indicate potential there is a significant rate of failure in medical research and development for compounds with promising cell data and any number of reasons as to why they may not work well enough in tissues or otherwise turn out to be infeasible for use in animals and humans
Posted by a reviewer on Amazon
Fisetin was one such senolytic candidate with cell study data only and i had not viewed it as a likely prospect
Posted by a reviewer on Amazon
It is a flavonoid and the one other wellknown possibly senolytic flavonoid turned out not to be useful on its own though it is helpful as a part of a combination treatment
Posted by a reviewer on Amazon
Per the data in the open access paper below dosing with fisetin destroys 2550 of senescent cells depending on organ and method of measurement
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